A `SummarizedExperiment` object created from gene expression and phenotypic data included in the ASURI package. The dataset included in ASURI as a stud case is intended to facilitate the use of the package. The dataset was obtained from several GSE series from [GEO database](http://www.ncbi.nlm.nih.gov/geo/) corresponding to breast cancer (BRCC) samples, where expression and survival time were reported [@Bueno2023]. Each sample corresponds to genome-wide expression profiles of BRCC primary tumor samples hybridized on the transcriptomic platform: *Affymetrix* *HGU133 Plus2.0*; which is a high-density microarray expression platform containing 594,000 oligo-nucleotide probes (organized in probe-sets) that we mapped to ENSEMBL genes using the *hgu133plus2hsensgcdf* CDF package, obtained from BRAINARRAY( hgu133plus2hsensgcdf_24.0.0.tar.gz.) The expression signal of the samples was normalized using fRMA [@fRMA] or RMA [@RMA] and Combat [@combat], as described in [@Bueno2023]. It integrates 1070 genes measured across 200 breast cancer samples with associated clinical annotations.

data(seBRCA)

Format

A `SummarizedExperiment` object with:

assay:

A matrix of normalized gene expression values (1070 genes × 200 samples).

colData:

A DataFrame with phenotypic variables for 200 samples.

Source

Derived from GEO datasets as described in [@Bueno2023].